Chemical Name: (2E,4E)-N-(2-Methylpropyl)-2,4-decadienamide
TRPV1 blocker
Molekulargewicht:
223.36
Reinheit:
>98% by TLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[18836-52-7]
Formel:
C14H25NO
Anwendungsbeschreibung:
Pellitorine (18836-52-7) is a weak TRPV1 blocker.1 Suppresses lipid accumulation in developing 3T3-L1 adipocytes.2 Inhibits LPS-induced production of TNFalpha and IL-6 and activation of NFkappaB in HUVECs at 10 µM.3 Inhibits free fatty acid uptake in Caco-2 cells.4 Inhibits LPS-induced nitric oxide production in RAW264.7 cells (IC50=14.5 µM) exhibiting anti-inflammatory activity by activation of the Nrf2/HO-1 pathway.5
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