Mocetinostat, CAS [[726169-73-9]]

Artikelnummer: FBM-10-3306
Artikelname: Mocetinostat, CAS [[726169-73-9]]
Artikelnummer: FBM-10-3306
Hersteller Artikelnummer: 10-3306
Alternativnummer: FBM-10-3306-5MG,FBM-10-3306-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: MGCD0103
Class I HDAC inhibitor
Molekulargewicht: 396.44
Reinheit: 98% by HPLC, NMR (Conforms)
Formulierung: Off-white solid
CAS Nummer: [726169-73-9]
Formel: C23H20N6O
Anwendungsbeschreibung: Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 µM for HDAC1, 2, 3 and 11 respectively.1 Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells.2 Displays antifibrotic effects in ischemic heart failure.3 Attenuates the development of hypersensitivity in models of neuropathic pain.4 Active in vivo.5