Mocetinostat, CAS [[726169-73-9]]

Produktübersicht

• Artikelname: Mocetinostat, CAS [[726169-73-9]]
• Artikelnummer: FBM-10-3306
• Hersteller Artikelnummer: 10-3306
• Alternativnummer: FBM-10-3306-5MG, FBM-10-3306-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide. Alternate Names: MGCD0103

Produktbeschreibung

Class I HDAC inhibitor

Produkteigenschaften

• Molekulargewicht: 396.44
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [726169-73-9]
• Formel: C23H20N6O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 µM for HDAC1, 2, 3 and 11 respectively.1 Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells.2 Displays antifibrotic effects in ischemic heart failure.3 Attenuates the development of hypersensitivity in models of neuropathic pain.4 Active in vivo.5