SCR7 pyrazine, CAS [[14892-97-8]]

Produktübersicht

• Artikelname: SCR7 pyrazine, CAS [[14892-97-8]]
• Artikelnummer: FBM-10-3652
• Hersteller Artikelnummer: 10-3652
• Alternativnummer: FBM-10-3652-5MG, FBM-10-3652-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone. Alternate Names: SCR7-G, SCR7-X

Produktbeschreibung

CRISPR enhancer

Produkteigenschaften

• Molekulargewicht: 332.38
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [14892-97-8]
• Formel: C18H12N4OS

Anwendungsbeschreibung

• Anwendungsbeschreibung: SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5