SLU-PP-332, CAS [[303760-60-3]]

Produktübersicht

• Artikelname: SLU-PP-332, CAS [[303760-60-3]]
• Artikelnummer: FBM-10-3948
• Hersteller Artikelnummer: 10-3948
• Alternativnummer: FBM-10-3948-10MG,FBM-10-3948-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: 4-Hydroxybenzoic acid 2-(2-naphthalenylmethylene)hydrazide, SR9861

Produktbeschreibung

pan-ERR agonist/Exercise mimetic

Produkteigenschaften

• Molekulargewicht: 290.32
• Reinheit: >98% by HPLC , NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [303760-60-3]
• Formel: C18H14N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Pan-agonist of the estrogen receptor-related receptors (EC50s cell-based cotransfection/reporter assay: ERRalpha = 98 nM, ERRß = 230 nM, ERRgamma = 430 nM) with highest potency for ERRalpha.1,2 SLU-PP-332 increased mitochondrial function and cellular respiration in a skeletal muscle cell line.2 It also increased fast oxidative skeletal muscle fibers (Type IIa) and exercise endurance in mice in an ERRalpha-specific manner. SLU-PP-332 activates an acute aerobic exercise genetic response via inducing the expression of DDIT4.2