PF-05089771, CAS [[1235403-62-9]]

Produktübersicht

• Artikelname: PF-05089771, CAS [[1235403-62-9]]
• Artikelnummer: FBM-10-3990
• Hersteller Artikelnummer: 10-3990
• Alternativnummer: FBM-10-3990-5MG,FBM-10-3990-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: PF771

Produktbeschreibung

Selective Nav1.7 channel blocker

Produkteigenschaften

• Molekulargewicht: 500.34
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1235403-62-9]
• Formel: C18H12Cl2FN5O3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of the voltage gated sodium channel 1.7 (Nav1.7).1,3 It is a state-dependent inhibitor with IC50 = 11 nM for the half-inactivated channels and IC50 ~ 10 µM for resting channels.1 Equipotent for human, monkey, dog, and mouse channels but 15x less potent for rat channels. Interacts equally with fast and slow inactivated Nav1.7 channels.2