Lomeguatrib, CAS [[192441-08-0]]

Produktübersicht

• Artikelname: Lomeguatrib, CAS [[192441-08-0]]
• Artikelnummer: FBM-10-4017
• Hersteller Artikelnummer: 10-4017
• Alternativnummer: FBM-10-4017-10MG,FBM-10-4017-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine. Alternate Names: O6-(4-Bromothenyl)guanine

Produktbeschreibung

MGMT inhibitor

Produkteigenschaften

• Molekulargewicht: 326.17
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: Off-white or beige solid
• CAS Nummer: [192441-08-0]
• Formel: C10H8BrN5O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.

Bilder

10-4017