UNC6934, CAS [[2561494-77-5]]

Produktübersicht

• Artikelname: UNC6934, CAS [[2561494-77-5]]
• Artikelnummer: FBM-10-4119
• Hersteller Artikelnummer: 10-4119
• Alternativnummer: FBM-10-4119-5MG, FBM-10-4119-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-Cyclopropyl-3-oxo-N-(4-pyrimidin-4-ylcarbamoyl)benzyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide

Produktbeschreibung

NSD2 inhibitor

Produkteigenschaften

• Molekulargewicht: 443.46
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [2561494-77-5]
• Formel: C24H21N5O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent (IC50 = 104 nM) and selective inhibitor of protein lysine methyltransferase nuclear receptor-binding SET domain-containing 2 (NSD2). It potently binds to the PWWP1 domain antagonizing interaction with nucleosomal H3K36me2. UNC6934 is selective against 14 other human PWWP domains and 33 methyltransferases. Active in a nanoBRET PPI assay in U2OS cells (IC50 = 1.23 µM).