2E151, CAS [[2416963-37-4]]

Produktübersicht

• Artikelname: 2E151, CAS [[2416963-37-4]]
• Artikelnummer: FBM-10-4145
• Hersteller Artikelnummer: 10-4145
• Alternativnummer: FBM-10-4145-10MG, FBM-10-4145-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[4-(2,5-Dimethylphenyl)-1,3-thiazol-2-yl]-4-(4-propylpiperidin-1-yl)sulfonylbenzamide

Produktbeschreibung

Vaccine co-adjuvant

Produkteigenschaften

• Molekulargewicht: 497.67
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2416963-37-4]
• Formel: C26H31N3O3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Vaccine adjuvants are materials that enhance the magnitude and duration of protective immune responses, typically via pattern recognition receptors (PRR). 2E151 is a co-adjuvant that increases the potency of toll-like receptor (TLR) adjuvants and overall enhances T cell stimulation/proliferation and cytokine production.1 It increases intracellular Ca2+ via extracellular Ca2+ influx, leading to NF-kB activation (EC50 = 0.9 µM)2 via IKK/MAPK phosphorylation and NFAT translocation in B cells and monocytes.