BD1063 dihydrochloride, CAS [[206996-13-6]]

Produktübersicht

• Artikelname: BD1063 dihydrochloride, CAS [[206996-13-6]]
• Artikelnummer: FBM-10-4211
• Hersteller Artikelnummer: 10-4211
• Alternativnummer: FBM-10-4211-5MG, FBM-10-4211-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride

Produktbeschreibung

Sigma-1 antagonist

Produkteigenschaften

• Molekulargewicht: 346.13
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [206996-13-6]
• Formel: C13H18Cl2N22HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: BD1063 is potent and selective sigma-1 antagonist (IC50s: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.