Chemical Name: 3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide. Alternate Names: 5-[3-[3,5-Bis(trifluoromethyl)phenyl]propyl]-1-oxidopyridin-1-ium-3-ol
GPR84 agonist
Molekulargewicht:
365.28
Reinheit:
>98% by HPLC, NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[3028055-45-7]
Formel:
C16H13F6NO2
Anwendungsbeschreibung:
OX04528 is a very potent (cAMP EC50 = 5.98 pM), selective (inactive at GPR40, GPR120, and CB2), and orally bioavailable GPR84 agonist with no detectable effects on ß-arrestin recruitment. A potent new chemical tool to probe the role of GPR84 in cancer, inflammatory, and fibrotic diseases.
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