Chemical Name: 3-[[(2R,3S)-2-[(1R)-1-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,4dihydro-1,2,4-triazol-5-one. Alternate Names: MK-0869, ONO-7436, L-754,030
NK-1 antagonist
Molekulargewicht:
534.43
Reinheit:
>98% by HPLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[170729-80-3]
Formel:
C23H21F7N4O3
Anwendungsbeschreibung:
Potent human neurokinin-1 (NK-1) antagonist.1 It is an FDA approved medication for the treatment of chemotherapy-induced and postoperative nausea and vomiting.2 Aprepitant is also a selective activator of the K2P channel TRAAK.3 It also has been shown to have multiple anticancer effects.4
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