Indoximod, CAS [[110117-83-4]]

Produktübersicht

• Artikelname: Indoximod, CAS [[110117-83-4]]
• Artikelnummer: FBM-10-4569
• Hersteller Artikelnummer: 10-4569
• Alternativnummer: FBM-10-4569-50MG,FBM-10-4569-250MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

IDO modulator / tryptophan mimetic

Produkteigenschaften

• Molekulargewicht: 218.25
• Reinheit: >98%, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [110117-83-4]
• Formel: C12H14N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Indoximod is a modulator of indoleamine 2,3-dioxygenase (IDO) activity.1 IDO can be used by tumors to avoid elimination by the host immune response2,3, thus inhibition of IDO is an interesting cancer therapeutic option. Indoximod is not a direct inhibitor of IDO, but instead targets the IDO gene leading to downstream effects.3 IDO-mediated catabolism of tryptophan inhibits the immunoregulatory kinases mTOR and PKC5. This is relieved by Indoximod acting as a potent tryptophan mimetic restoring mTOR and PKC signaling.4