Nitazoxanide, CAS [[55981-09-4]]

Produktübersicht

• Artikelname: Nitazoxanide, CAS [[55981-09-4]]
• Artikelnummer: FBM-10-4633
• Hersteller Artikelnummer: 10-4633
• Alternativnummer: FBM-10-4633-10MG, FBM-10-4633-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: O-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenyl acetate

Produktbeschreibung

Antiviral and antiparasitic agent

Produkteigenschaften

• Molekulargewicht: 307.28
• Reinheit: 99% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [55981-09-4]
• Formel: C12H9N3O5S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Nitazoxanide is a clinically relevant antiparasitic agent.1It has since been repurposed as a broad-spectrum antiviral agent that is active against many RNA and DNA viruses including influenza, Hepatitis B and C, RSV, coronavirus, dengue and others.2 Its antiparasitic activity is believed to be due to inhibition of pyruvate:ferredoxin/flavodoxin oxidoreductases.3 Antiviral activity involves activation of protein kinase activated by double-stranded RNA (PKR) leading to phosphorylation of eukaryotic initiation factor 2 alpha (eIF2alpha).4 Nitazoxanide has also been found to inhibit Wnt signaling independent of adenomatous polyposis coli (APC) - it targets peptidyl arginine deiminase 2 (PAD2) resulting in increased citrullination of beta-catenin.5