NG52, CAS [[212779-48-1]]

Produktübersicht

• Artikelname: NG52, CAS [[212779-48-1]]
• Artikelnummer: FBM-10-4681
• Hersteller Artikelnummer: 10-4681
• Alternativnummer: FBM-10-4681-5MG,FBM-10-4681-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Phosphoglycerate kinase 1 inhibitor

Produkteigenschaften

• Molekulargewicht: 346.82
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [212779-48-1]
• Formel: C16H19ClN6O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Inhibitor of Cdc2-cyclin B (IC50 = 340 nM) as well as Cdc28p (IC50 = 7 µM) and Pho85p (IC50 = 2 µM).1 It inhibited phosphoglycerate kinase 1 (IC50 = 2.5 µM) and inhibited the proliferation of glioma U87 and U251 cell lines via reversal of the Warburg effect.2 NG52 inhibited the proliferation, increased apoptosis, and reduced the migration and invasive ability of OVCAR3 and ES-2 ovarian cancer cell lines via suppression of glycolytic capability.3