Glumetinib, CAS [[1642581-63-2]]

Produktübersicht

• Artikelname: Glumetinib, CAS [[1642581-63-2]]
• Artikelnummer: FBM-10-4690
• Hersteller Artikelnummer: 10-4690
• Alternativnummer: FBM-10-4690-5MG, FBM-10-4690-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 6-(1-Methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-yl]sulfonylpyrazolo[4,3-b]pyridine. Alternate Names: SCC244

Produktbeschreibung

Highly selective c-Met inhibitor

Produkteigenschaften

• Molekulargewicht: 459.48
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [1642581-63-2]
• Formel: C21H17N9O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.