Chemical Name: 3,7-Dihydropurine-6-thione monohydrate. Alternate Names: 6-MP
Purine antimetabolite and immunomodulator
Molekulargewicht:
170.19
Reinheit:
>98% by HPLC NMR (Conforms)
Formulierung:
Yellow solid
CAS Nummer:
[6112-76-1]
Formel:
C5H4N4SH2O
Anwendungsbeschreibung:
Purine antimetabolite drug used to treat acute lymphocytic leukemia, Crohns disease, ulcerative colitis, and inflammatory bowel disease.1 It inhibits DNA synthesis by inhibiting the production of purine containing nucleotides. The immunomodulatory activity of 6-Mercaptopurine is mainly the result of the 6-MP metabolite 6-thioguanine triphosphate (6-TGTP) binding to small GTPase Rac1.2
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