KC7F2, CAS [[927822-86-4]]

Produktübersicht

• Artikelname: KC7F2, CAS [[927822-86-4]]
• Artikelnummer: FBM-10-4714
• Hersteller Artikelnummer: 10-4714
• Alternativnummer: FBM-10-4714-10MG, FBM-10-4714-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N,N-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide

Produktbeschreibung

HIF-1alpha inhibitor

Produkteigenschaften

• Molekulargewicht: 570.38
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [927822-86-4]
• Formel: C16H16Cl4N2O4S4

Anwendungsbeschreibung

• Anwendungsbeschreibung: KC7F2 is an inhibitor of HIF-1alpha (IC50 = 20 µM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1alpha protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1alpha protein synthesis.