SNS-314 mesylate, CAS [[1146618-41-8]]

Produktübersicht

• Artikelname: SNS-314 mesylate, CAS [[1146618-41-8]]
• Artikelnummer: FBM-10-4779
• Hersteller Artikelnummer: 10-4779
• Alternativnummer: FBM-10-4779-5MG, FBM-10-4779-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate

Produktbeschreibung

Aurora kinase inhibitor

Produkteigenschaften

• Molekulargewicht: 527.04
• Reinheit: 98% by HPLC NMR (conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1146618-41-8]
• Formel: C18H15ClN6OS2CH3SO3H

Anwendungsbeschreibung

• Anwendungsbeschreibung: SNS-314 is a potent and selective pan-Aurora kinase inhibitor (IC50s: Aurora A = 9 nM, Aurora B = 31 nM, Aurora C = 3 nM.1,2 It was able to inhibit proliferation in a wide panel of human cancer cell lines including colon (HCT116), breast (MDA-MB-231), prostate (PC-3), lung (H1299, Calu-6), ovarian (A2780), melanoma (A375) and liver (SMMC-7721, HepG2, LM6).1-4