JNK-IN-8, CAS [[1410880-22-6]]

Produktübersicht

• Artikelname: JNK-IN-8, CAS [[1410880-22-6]]
• Artikelnummer: FBM-10-4780
• Hersteller Artikelnummer: 10-4780
• Alternativnummer: FBM-10-4780-5MG, FBM-10-4780-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-[[4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]-N-[3-methyl-4-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Alternate Names: JNK Inhibitor XVI

Produktbeschreibung

JNK inhibitor

Produkteigenschaften

• Molekulargewicht: 507.60
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [1410880-22-6]
• Formel: C29H29N7O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively).1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3