LDN-192960 HCl, CAS [[184582-62-5]]

Produktübersicht

• Artikelname: LDN-192960 HCl, CAS [[184582-62-5]]
• Artikelnummer: FBM-10-4836
• Hersteller Artikelnummer: 10-4836
• Alternativnummer: FBM-10-4836-5MG, FBM-10-4836-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride

Produktbeschreibung

Haspin and DYRK2/3 inhibitor

Produkteigenschaften

• Molekulargewicht: 401.35
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [184582-62-5]
• Formel: C18H20N2O2S2HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3