GSK872, CAS [[1346546-69-7]]

Produktübersicht

• Artikelname: GSK872, CAS [[1346546-69-7]]
• Artikelnummer: FBM-10-4861
• Hersteller Artikelnummer: 10-4861
• Alternativnummer: FBM-10-4861-5MG, FBM-10-4861-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-(6-Propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine. Alternate Names: GSK2399872A, GSK872

Produktbeschreibung

Necroptosis inhibitor / RIP3 inhibitor

Produkteigenschaften

• Molekulargewicht: 383.49
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white or pale yellow solid
• CAS Nummer: [1346546-69-7]
• Formel: C19H17N3O2S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: GSK872 is a potent (IC50 = 1.8nM domain binding, IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 µM).2