Olutasidenib, CAS [[1887014-12-1]]
Artikelnummer:
FBM-10-4917
| Artikelname: |
Olutasidenib, CAS [[1887014-12-1]] |
| Artikelnummer: |
FBM-10-4917 |
| Hersteller Artikelnummer: |
10-4917 |
| Alternativnummer: |
FBM-10-4917-5MG,FBM-10-4917-25MG |
| Hersteller: |
Focus Biomolecules |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
FT-2102 |
| Molekulargewicht: |
354.79 |
| Reinheit: |
>98% by HPLC NMR (Conforms) |
| Formulierung: |
Off-white solid |
| CAS Nummer: |
[1887014-12-1] |
| Formel: |
C18H15ClN4O2 |
| Anwendungsbeschreibung: |
Olutasidenib is a potent (IC50s cell-based IDH1 mutants: HCT116-R132H = 21 nM, HCT116-IDH-R132C = 94 nM, U87MG-R132L = 42 nM, U87MG-R132G = 6 nM, U87MG-R132S = 9 nM) and CNS-penetrant mutant isocitrate dehydrogenase 1 inhibitor.1 It induced durable and complete remissions in relapsed or refractory IDH1 mutated acute myeloid leukemia.2,3 |
