Chemical Name: (6S)-1-[[4-(Dimethylamino)-3-methylphenylmethyl]-5-(2,2diphenylacetyl)-6,7-dihydro-4H-imidazo[4,5-c]pyridine-6-carboxylic acid ditrifluoroacetate
Angiotensin II type II antagonist
Molekulargewicht:
736.66
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
Yellow solid
CAS Nummer:
[136676-91-0]
Formel:
C31H32N4O32CF3CO2H
Anwendungsbeschreibung:
Potent (IC50 = 34 nM) and selective non-peptide angiotensin II type 2 (AT2) antagonist.1 Ameliorated symptoms of 2,4-dinitrobenzenesulfonic-induced colitis in rats via inhibition of NF-kB activation.2 PD123319 displayed protective effects in ischemia-reperfusion injury and oxidative damage in rat hearts.3
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