GKT-137831, CAS [[1218942-37-0]]
Artikelnummer:
FBM-10-5044
| Artikelname: |
GKT-137831, CAS [[1218942-37-0]] |
| Artikelnummer: |
FBM-10-5044 |
| Hersteller Artikelnummer: |
10-5044 |
| Alternativnummer: |
FBM-10-5044-5MG,FBM-10-5044-25MG |
| Hersteller: |
Focus Biomolecules |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
Setanaxib, GKT-831 |
| NADPH oxidase NOX1/4 inhibitor |
| Molekulargewicht: |
394.85 |
| Reinheit: |
98% by TLC NMR (Conforms) |
| Formulierung: |
Pale-yellow solid |
| CAS Nummer: |
[1218942-37-0] |
| Formel: |
C21H19ClN4O2 |
| Anwendungsbeschreibung: |
NADPH oxidase, NOX1/4 inhibitor (Ki = 100-150 nM).1 Inhibits erastin-stimulated ROS production.2 Potentiates immunotherapy by overcoming cancer-associated fibroblast- mediated CD8+ T-cell exclusion.3 Reduces ROS production in LPS-stimulated platelets in a mouse model.4 Reduces subarachnoid hemorrhage-induced neuronal death.5 Potent inhibitor of experimental liver fibrosis in mouse models.6 |
