Remodelin, CAS [[949912-58-7]]

Produktübersicht

• Artikelname: Remodelin, CAS [[949912-58-7]]
• Artikelnummer: FBM-10-5085
• Hersteller Artikelnummer: 10-5085
• Alternativnummer: FBM-10-5085-5MG, FBM-10-5085-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile

Produktbeschreibung

Acetyl-transferase NAT10 inhibitor

Produkteigenschaften

• Molekulargewicht: 282.36
• Reinheit: 98% by HPLC NMR (conforms)
• Formulierung: Pale yellow solid
• CAS Nummer: [949912-58-7]
• Formel: C15H14N4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent and selective inhibitor of N-acetyltransferase 10 (NAT10) which is capable of acetylating microtubules and histones.1 Improves nuclear architecture, chromatin organization and fitness of both human lamin A/C-depleted cells and Hutchinson-Gilford progeria syndrome patient cells1, normalizing progeric and aging cells2. Enhances health span in a mouse model of human accelerated aging syndrome.3 Significantly reduces many of the defects associated with accumulation of the lamin A precursor, prelamin A.4 Inhibits NAT10-promoted metastasis which may be mediated by endothelial-to-mesenchymal transition in hepatocellular carcinoma.5