Chemical Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine, tartrate. Alternate Names: LY246708 tartrate
Selective M1 Muscarinic agonist
Molekulargewicht:
431.50
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
Off-white solid
CAS Nummer:
[152854-19-8]
Formel:
C14H23N3OS
Anwendungsbeschreibung:
A functionally-selective M1 muscarinic receptor agonist, EC50=0.3, 92.5, 5, 52 and 42 nM for M1, M2, M3, M4 and M5 respectively.1,2 Displays positive cognitive and behavioral effects in schizophrenia and Alzheimers disease.3 Suppresses proinflammatory cytokine responses and improves survival in sepsis.4 Displays potent analgesic activity in rodent models of chronic inflammatory and neuropathic pain.5
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