Chemical Name: N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-carbamic acid , 2,6-dimethylphenyl ester
Src family inhibitor
Molekulargewicht:
568.67
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
White or off-white solid
CAS Nummer:
[837422-57-8]
Formel:
C32H36N6O4
Anwendungsbeschreibung:
A potent and selective inhibitor of Src family kinases Lck and Src, IC50=2 and 6 nM respectively.1,2 Also inhibits SIK, IC50=10, 22 and 60 nM for SIK 1, 2 and 3 respectively.3 May be used along with PD-325901 and CHIR-99021 to support self-renewal of naive human embryonic stem cells.4
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