MreB Inhibitor A22, CAS [[22816-60-0]]

Produktübersicht

• Artikelname: MreB Inhibitor A22, CAS [[22816-60-0]]
• Artikelnummer: FBM-10-5275
• Hersteller Artikelnummer: 10-5275
• Alternativnummer: FBM-10-5275-10MG,FBM-10-5275-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: MreB Purturbing Compound A22

Produktbeschreibung

Disrupts bacterial actin cytoskeleton

Produkteigenschaften

• Molekulargewicht: 271.58
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [22816-60-0]
• Formel: C8H8Cl2N2S HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: A22 disrupts the actin cytoskeleton of bacteria causing defects in morphology and chromosome segregation.1 It is a competitive inhibitor of ATP binding to MreB and has the ability to disassemble the actin cytoskeleton in bacterial cells.1 It displays antibacterial activity against P. aeruginosa (among many others) including multidrug-resistant clinical isolates and points to MreB as a new target for antibacterial development.2 A22 significantly disrupts biofilm formation by interfering with the ability of bacterial cells to maintain shape and adherence to surfaces.3