Ascochlorin, CAS [[26166-39-2]]

Produktübersicht

• Artikelname: Ascochlorin, CAS [[26166-39-2]]
• Artikelnummer: FBM-10-5296
• Hersteller Artikelnummer: 10-5296
• Alternativnummer: FBM-10-5296-100UG,FBM-10-5296-500UG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Ilicicolin D, NSC 287492

Produktbeschreibung

Mitochondrial cytochrome bc1 complex inhibitor

Produkteigenschaften

• Molekulargewicht: 404.93
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [26166-39-2]
• Formel: C23H29ClO4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Ascochlorin is a novel isoprenoid phenol isolated from Acremonium egyptiacum and other species.1 It is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex (mitochondrial respiratory chain complex III) acting at both active sites.2 It induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages3 resulting in anti-inflammatory effects4. Demonstrates substantial antineoplastic effects in a variety of tumor cell lines and mouse models.5