CEP, CAS [[1838570-66-3]]

Produktübersicht

• Artikelname: CEP, CAS [[1838570-66-3]]
• Artikelnummer: FBM-10-5323
• Hersteller Artikelnummer: 10-5323
• Alternativnummer: FBM-10-5323-5MG, FBM-10-5323-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2,3-Dichloro-7-(2-propynyl)-7H-purine

Produktbeschreibung

Protein-RNA binding click probe

Produkteigenschaften

• Molekulargewicht: 227.05
• Reinheit: >98% by TLC, NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1838570-66-3]
• Formel: C8H4Cl2N4

Anwendungsbeschreibung

• Anwendungsbeschreibung: CEP (1838570-66-3) is a clickable electrophilic purine which may be used to directly quantify protein-RNA interaction on proteins via photoaffinity competition with 4-thiouridine-labeled RNA in cells. Employing CEP in a photo-activatable-competition and chemoproteomic enrichment (PACCE) protocol enables functional profiling of canonical RNA-binding domains as well as the discovery of ''moonlighting RNA binding activity in the human proteome. This new methodology represents a chemoproteomic platform for global quantification of protein-RNA binding activity in living cells.