Chemical Name: (1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-1- phenanthrenecarboxylic acid
Potassium channel activator
Molekulargewicht:
302.45
Reinheit:
98% by GC, TLC NMR (conforms)
Formulierung:
White solid
CAS Nummer:
[5835-26-7]
Formel:
C20H30O2
Anwendungsbeschreibung:
Terpenoid acid that activates BK (voltage-gated potassium) channels when used at 10 µM in HEK293 cells.1 Improves spatial and non-spatial memory in Alzheimers mouse model2,3, and significantly improves motor function in a rat spinal cord injury model4. Reduces hyperactivity of spontaneously active auditory networks, EC50=7.8 M.5
10-5487
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