CR8 3HCl (R), CAS [[294646-77-8]]

Produktübersicht

• Artikelname: CR8 3HCl (R), CAS [[294646-77-8]]
• Artikelnummer: FBM-10-5507
• Hersteller Artikelnummer: 10-5507
• Alternativnummer: FBM-10-5507-5MG, FBM-10-5507-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (R)-2-((9-Isopropyl-6-((4-(pyridin-2-yl)benzyl)amino)-9H-purin-2-yl)amino)butan-1-ol

Produktbeschreibung

CDK inhibitor

Produkteigenschaften

• Molekulargewicht: 540.91
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White or off-white solid
• CAS Nummer: [294646-77-8]
• Formel: C24H29N7O 3HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: Second generation analog of roscovitine which inhibits cyclin-dependent kinases with increased potency, Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5, p25, and Cdk9/cyclin T, IC50s=0.09, 0.072, 0.041, 0.11 and 0.18 M respectively.1,2 Acts as a molecular glue degrader that depletes cyclin K.3 CR8 displays neuroprotective effects in various models including traumatic brain injury.4