AM-580, CAS [[102121-60-8]]

Produktübersicht

• Artikelname: AM-580, CAS [[102121-60-8]]
• Artikelnummer: FBM-10-5511
• Hersteller Artikelnummer: 10-5511
• Alternativnummer: FBM-10-5511-5MG,FBM-10-5511-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: CD336, NSC 608001, Ro 40-6055

Produktbeschreibung

RARalpha agonist

Produkteigenschaften

• Molekulargewicht: 351.45
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [102121-60-8]
• Formel: C22H25NO3

Anwendungsbeschreibung

• Anwendungsbeschreibung: Retinoic acid analog acting as a RARalpha agonist (Kd = 8 nM).1 Induces or blocks differentiation depending on cell type and environment.2,3 In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures.4 AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.5,6