Chemical Name: N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine, 2,4,6-Tris(dimethylamino)-1,3,5-triazine. Alternate Names: Hexamethylmelamine, NSC-13875
GPX4 inhibitor, Ferroptosis inducer
Molekulargewicht:
210.29
Reinheit:
>98% by TLC NMR (Conforms)
Formulierung:
White solid
CAS Nummer:
[645-05-6]
Formel:
C9H18N6
Anwendungsbeschreibung:
Induces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides.1 Ferroptosis induction may be its mechanism of action as a cancer chemotherapeutic.2 Clinically useful agent for ovarian cancer.3,4
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