TTK21, CAS [[709676-56-2]]

Produktübersicht

• Artikelname: TTK21, CAS [[709676-56-2]]
• Artikelnummer: FBM-10-5669
• Hersteller Artikelnummer: 10-5669
• Alternativnummer: FBM-10-5669-5MG, FBM-10-5669-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-propoxybenzamide

Produktbeschreibung

CBP/p300 histone acetyltransferase activator

Produkteigenschaften

• Molekulargewicht: 357.76
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [709676-56-2]
• Formel: C17H15ClF3NO2

Anwendungsbeschreibung

• Anwendungsbeschreibung: TTK21 (709676-56-2) is a novel activator of CBP/p300 acetyl transferases.1 When TTK21 is conjugated to glucose-based carbon nanospheres (CSP) it is nontoxic and is BBB permeable. CSP-TTK21, upon intraperitoneal administration to mice, acetylated histones in the hippocampus and frontal cortex and increased BDNF levels.1 It reinstated plasticity and memory in a tauopathy mouse model2, ameliorated Abeta-impaired long term potentiation3 and promoted axon growth, sprouting and synaptic plasticity in chronic experimental spinal cord injury4.