Exatecan mesylate, CAS [[169869-90-3]]

Produktübersicht

• Artikelname: Exatecan mesylate, CAS [[169869-90-3]]
• Artikelnummer: FBM-10-5764
• Hersteller Artikelnummer: 10-5764
• Alternativnummer: FBM-10-5764-20MG, FBM-10-5764-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13-dione, methanesulfonate. Alternate Names: DX-8951f

Produktbeschreibung

Topoisomerase I inhibitor

Produkteigenschaften

• Molekulargewicht: 531.56
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Grey solid
• CAS Nummer: [169869-90-3]
• Formel: C24H22FN3 O4 CH3SO3H

Anwendungsbeschreibung

• Anwendungsbeschreibung: Exatecan mesylate is a hexacyclic, water soluble camptothecin analog exhibiting potent antitumor activity in vitro and in vivo.1 It is a potent topoisomerase I inhibitor displaying antiproliferative activity against 32 malignant cell lines and was shown to be 6 and 28 times more potent than SN-38 and topotecan respectively1. It displays potent cytotoxic effects in various drug-resistant cells.2 Exatecan can be utilized as a cytotoxic payload in the development of novel antibody drug conjugates (ADCs).3