Caspase-1/3/8/9/10/12 Inhibitor Plus, Q-VD-OPh

Artikelnummer: GTX-GTX47939
Artikelname: Caspase-1/3/8/9/10/12 Inhibitor Plus, Q-VD-OPh
Artikelnummer: GTX-GTX47939
Hersteller Artikelnummer: GTX47939
Alternativnummer: GTX47939-1
Hersteller: GeneTex
Kategorie: Biochemikalien
Applikation: Neutralizing/Inhibition
Alternative Synonym: Caspase-1 inhibitor Caspase-3 inhibitor Caspase-8 inhibitor C , Quinolyl-Val-Asp-Oph , Caspase1 inhibitor Caspase3 inhibitor Caspase8 inhibitor C , Caspase Inhibitor , QuinolylValAspOph , QValAspOph , Quinolyl Val Asp Oph
Konzentration: 10 mg/ml (Please refer to the vial label for the specific concentration.)
Molekulargewicht: 513
Puffer: In DMSO (10 mM solution)
Lagerung: -20°C
Target-Kategorie: Next generation cell permeable peptide inhibitor for Caspase family
Application Verdünnung: We recommend a working concentration of 1-10 uM for in vitro studies.
Anwendungsbeschreibung: We recommend a working concentration of 1-10 uM for in vitro studies.
Inhibition of Caspase-3 activity by next generation caspase inhibitor, Q-VD-OPh: Different concentrations of inhibitor Q-VD-OPh were tested to check the inhibition of Caspase-3 activity. Active Caspase-3 was incubated with the inhibitor Q-VD-OPh for 7 min prior to addition of synthetic peptide substrate DEVD-AFC (AFC,7-amino-4-trifluoromethyl coumarin). Fluorescence was measured at Ex/Em = 400/505 nm.