Human PD-L1 protein, mouse IgG1 Fc tag (active), Unconjugated

Artikelnummer: GTX01279-PRO
Artikelname: Human PD-L1 protein, mouse IgG1 Fc tag (active), Unconjugated
Artikelnummer: GTX01279-PRO
Hersteller Artikelnummer: GTX01279-pro
Alternativnummer: GTX01279-PRO-100
Hersteller: GeneTex
Kategorie: Proteine/Peptide
Applikation: FA
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1
NCBI: 29126
UniProt: Q9NZQ7
Puffer: Batch dependent (please contact us for details)
Expression System: HEK293 cells
Formulierung: Lyophilized powder
Sequenz: C-terminal mouse IgG1-Fc tagged, Met1-Thr239 of Human PD-L1 protein (NP_054862.1)
Anwendungsbeschreibung: 1. Measured by its binding ability in a functional ELISA. Immobilized recombinant Human PD1-His protein at 10 µg/ml (100 µl/well) can bind Human PD-L1 protein (active) (GTX01279-pro) with a linear range of 1.28-20 µg/ml.2. Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T cell lymphocytes. The ED50 for this effect is typically 0.4-3 µg/ml.