The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin alphafamily. CD49b, also known as integrin alphaalpha2, associates non-covalently with CD29 (integrin alphabeta1) to form the VLA-2 heterodimer. VLA-2 integrin alphas function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
Klonalität:
Monoclonal
Konzentration:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)