CD40L / CD154 antibody [5C8], IgG2a, Unconjugated, Mouse, Monoclonal

Produktübersicht

• Artikelname: CD40L / CD154 antibody [5C8], IgG2a, Unconjugated, Mouse, Monoclonal
• Artikelnummer: GTX01484
• Hersteller Artikelnummer: GTX01484
• Alternativnummer: GTX01484-100
• Hersteller: GeneTex
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human, Primate
• Konjugation: Unconjugated
• Alternative Synonym: CD40 ligand , CD154 , CD40L , CD40LG , HIGM1 , IGM , IMD3 , TBAM , TNFSF5 , TRAP , gp39 , hCD40L

Produktbeschreibung

The 5C8 antibody reacts with human CD154 which is also known as CD40L (CD40 ligand). CD154 is a 39kDa member of the TNF-alpha superfamily and is predominantly expressed on activated T cells but is also expressed on NK cells, mast cells, basophils, and eosinophils. CD154 binds to CD40, a molecule that is expressed on antigen presenting cells including B cells, monocytes/macrophages, and dendritic cells. The interaction of CD154 and CD40 regulates the activation of antigen presenting cells and is critical for B cell costimulation. The 5C8 antibody has been reported to block CD40L-CD40 interactions.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
• Klon-Bezeichnung: [5C8]
• Isotyp: IgG2a
• NCBI: 959
• UniProt: P29965
• Puffer: 10mM NaH2PO4, 150mM NaCl, 0.09% Sodium azide.
• Formulierung: Liquid

Anwendungsbeschreibung

• Anwendungsbeschreibung: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.