FOXP3 antibody [MF23] (APC), IgG2b, Rat, Monoclonal
Artikelnummer:
GTX01488-07
Hersteller Artikelnummer:
GTX01488-07
Alternativnummer:
GTX01488-07-100
Hersteller:
GeneTex
Wirt:
Rat
Kategorie:
Antikörper
Applikation:
FC
Spezies Reaktivität:
Mouse
Konjugation:
APC
The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Klonalität:
Monoclonal
Konzentration:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
