Batimastat is a potent, broad spectrum MMP inhibitor with IC50s values of 3, 4, 4, 6 and 20 nM for MMPs -1, -2, -9, -7 and -3 respectively. Metalloproteinases play a necessary role in invasion and angiogenesis and batimastat exhibits antiproliferative, anti-invasive and antimetastatic activity in human colon, ovarian and prostate xenografts. Batimastat attenuates neuroinflammation following focal cerebral ischemia in mice.
Molekulargewicht:
477.64
Reinheit:
98% by HPLC, NMR conforms
Formulierung:
White solid
CAS Nummer:
[130370-60-4]
Formel:
C23H31N3O4S2
Target-Kategorie:
Matrix metalloproteases
Anwendungsbeschreibung:
ProductType: Small molecules
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