736-745-TAT, also known as TAT-TRPV1(736-745), is a cell permeable TRPV1 fragment that can inhibit the interaction of TRPV1 and AKAP79. 736-745-TAT consists of amino acids 736-749 from the TRPV1 C-terminal domain, combined with amino acids 47-57 of TAT to promote uptake across neuronal cell membranes. 736-745-TAT inhibits both the first and the second phase of pain behaviour in the formalin test, implying an effect on both acute and inflammatory pain.
