A11

Produktübersicht

• Artikelname: A11
• Artikelnummer: ISC-PP-250
• Hersteller Artikelnummer: PP-250
• Alternativnummer: ISC-PP-250
• Hersteller: Isca Biochemicals
• Kategorie: Biochemikalien
• Alternative Synonym: ANXA1-derived 11 amino acid -long peptide

Produktbeschreibung

A11 is a peptide derived from amino acid residues 20-30 of the ANXA1 N-terminus fused to the cell penetrating peptide CPP. A11 blocks ANXA1 competition with the E3 ubiquitin ligase Cbl for binding EphA2, enhancing Cbl-mediated EphA2 ubiquitination and degradation, and reducing the oncogenic mechanism of the ANXA1 - EphA2 interaction in nasopharyngeal carcinoma (NPC). A11 can suppress NPC cell growth in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 2767.19
• NCBI: 2020
• Reinheit: >95% by hplc
• Formulierung: Freeze dried solid
• Sequenz: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Glu-Tyr-Val-Gln-Thr-Val-Lys-Ser-Ser-Lys-Gly-OH
• Formel: C117H204N46O32
• Target-Kategorie: Protein-protein interactions

Anwendungsbeschreibung

• Anwendungsbeschreibung: ProductType: Cell penetrating peptides