Human CD19 Protein (CD1-HM119)

Produktübersicht

• Artikelname: Human CD19 Protein (CD1-HM119)
• Artikelnummer: KAB-CD1-HM119
• Hersteller Artikelnummer: CD1-HM119
• Alternativnummer: KAB-CD1-HM119-100UG, KAB-CD1-HM119-500UG
• Hersteller: KactusBio
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: CD19, B4, CVID3, Leu-12, MGC12802

Produktbeschreibung

Recombinant Human CD19 Protein is expressed from HEK293 with His tag at the C-Terminus, It contains Pro20-Lys291.

Produkteigenschaften

• Molekulargewicht: The protein has a predicted MW of 34.7 kDa. Due to glycosylation, the protein migrates to 50-60 KDa based on Bis-Tris PAGE result.
• Tag: C-His
• UniProt: P15391
• Puffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Reinheit: >95% as determined by Bis-Tris PAGE
• Formulierung: Lyophilized
• Sequenz: Pro20-Lys291
• Target-Kategorie: CD19

Bilder

Human CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human CD19, His Tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for Inebilizumab, hFc Tag with the EC50 of 8.5 ng/ml determined by ELISA.

Immobilized Human CD19, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Denintuzumab, hFc Tag with the EC50 of 8.6 ng/ml determined by ELISA.

Immobilized Human CD19, His Tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for Coltuximab, hFc Tag with the EC50 of 6.3 ng/ml determined by ELISA (QC Test).

Immobilized Human CD19, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for FMC63, mFc Tag with the EC50 of 11.1 ng/ml determined by ELISA (QC Test).

Anti-CD19 Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human CD19, His Tag with an affinity constant of 0.50 nM as determined in SPR assay (Biacore T200).

Loaded Denintuzumab, hFc Tag on ProA-Biosensor, can bind Human CD19, His Tag with an affinity constant of 3.73 nM as determined in BLI assay (Gator).

Loaded Inebilizumab on ProA-Biosensor can bind Human CD19, His Tag with an affinity constant of 8.03 nM as determined in BLI assay (Gator Prime).

Loaded Coltuximab on ProA-Biosensor can bind Human CD19, His Tag with an affinity constant of 5.65 nM as determined in BLI assay (Gator Prime).

Loaded FMC63 on MFc-Biosensor can bind Human CD19, His Tag with an affinity constant of 1.44 nM as determined in BLI assay (Gator Prime).