Cynomolgus/Rhesus macaque FcRn Protein (FRN-CM101)

Produktübersicht

• Artikelname: Cynomolgus/Rhesus macaque FcRn Protein (FRN-CM101)
• Artikelnummer: KAB-FRN-CM101
• Hersteller Artikelnummer: FRN-CM101
• Alternativnummer: KAB-FRN-CM101-100UG, KAB-FRN-CM101-500UG
• Hersteller: KactusBio
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Alternative Synonym: FcRn alpha chain, FCGRT, FCRN, FCGRT&B2M

Produktbeschreibung

Recombinant Cynomolgus/Rhesus macaque FcRn Protein is expressed from HEK293 with His tag at the C-Terminus of FCGRT.It contains Ala24-Ser297 (FCGRT) and Ile21-Met119 (B2M).

Produkteigenschaften

• Molekulargewicht: The protein has a predicted MW of 31.5 kDa (FCGRT) and 11.6 kDa (B2M). Due to glycosylation, the protein migrates to 35-38 kDa (FCGRT) and 13-15 kDa (B2M) based on Bis-Tris PAGE result.
• Tag: C-His
• UniProt: Q8SPV9
• Puffer: Lyophilized from 0.22 µm filtered solution in 20mM PB, 250mM NaC (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Reinheit: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Formulierung: Lyophilized
• Sequenz: Ala24-Ser297(FCGRT) & Ile21-Met119(B2M)
• Target-Kategorie: FcRn

Bilder

Cynomolgus/Rhesus macaque FcRn on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus/Rhesus macaque FcRn is greater than 95% as determined by SEC-HPLC.

Cynomolgus/Rhesus macaque FcRn, His Tag captured on CM5 Chip via Anti-His Antibody can bind Trastuzumab with an affinity constant of 0.18 uM as determined in SPR assay (Biacore T200).

Immobilized Cynomolgus/Rhesus macaque FcRn, His Tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-FcRn Antibody, hFc Tag with the EC50 of 8.0 ng/ml determined by ELISA (QC Test).

Cynomolgus Serum Albumin, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque FcRn, His Tag with an affinity constant of 0.13 uM as determined in SPR assay (Biacore T200).