Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori[1][2][3].
Molekulargewicht:
381.85
Reinheit:
99.41
CAS Nummer:
[1957202-44-6]
Formel:
C17H17ClFN3O2S
Target-Kategorie:
Bacterial,Proton Pump
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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