Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].
Molekulargewicht:
458.08
CAS Nummer:
[133825-81-7]
Formel:
C27H40ClN3O
Target-Kategorie:
Acyltransferase,Apoptosis,Reference Standards
Anwendungsbeschreibung:
Reference Standards
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