Pactimibe, CAS [[189198-30-9]]

Produktübersicht

• Artikelname: Pactimibe, CAS [[189198-30-9]]
• Artikelnummer: MCE-HY-100401
• Hersteller Artikelnummer: HY-100401
• Alternativnummer: MCE-HY-100401-10MG,MCE-HY-100401-5MG,MCE-HY-100401-50MG,MCE-HY-100401-25MG,MCE-HY-100401-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CS-505 (free base)

Produktbeschreibung

Pactimibe (CS-505 free base) is a dual ACAT1/2 inhibitor with IC50s of 4.9 µM and 3.0 µM, respectively. Pactimibe (CS-505 free base) inhibits ACAT with IC50s of 2.0 µM, 2.7 µM, 4.7 µM in the liver, macrophages and THP-1 cells, respectively[1]. Pactimibe (CS-505 free base) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 µM. Moreover, Pactimibe (CS-505 free base) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 µM. Pactimibe (CS-505 free base) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity[2].

Produkteigenschaften

• Molekulargewicht: 416.60
• Reinheit: 99.98
• CAS Nummer: [189198-30-9]
• Formel: C25H40N2O3
• Target-Kategorie: Acyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound