Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 µM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases[1].
Molekulargewicht:
367.44
Reinheit:
99.78
CAS Nummer:
[261944-46-1]
Formel:
C21H25N3O3
Target-Kategorie:
Proton Pump
Anwendungsbeschreibung:
Reference compound
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